North American Familial Chylomicronemia Syndrome Score (NAFCS Score)
Clinical diagnostic score to help distinguish classical familial chylomicronemia syndrome from multifactorial chylomicronemia syndrome.
INSTRUCTIONS
Apply it in patients with severe hypertriglyceridemia; for patients aged 10 years or older, the published score assumes nonresponse to fibrates or high-dose omega-3 fatty acids.
Current age*
<1 yearA
1-9 yearsB
≥10 yearsC
HTG onset*
<10 yearsA
≥10 yearsB
Body mass index*
≥25 kg/m² or ≥85th percentile0
<25 kg/m² or <85th percentile+9
History of abdominal pain or pancreatitis*
Neither abdominal pain nor pancreatitis0
Abdominal pain but no pancreatitis+9
Pancreatitis+16
Presence of secondary factors that may contribute to HTG*
All recent fasting TG readings >10 mmol/L (>880 mg/dL)*
