Uses the PLASMIC score to support distinction between probable aHUS and severe ADAMTS13 deficiency / probable TTP in patients with confirmed thrombotic microangiopathy.
INSTRUCTIONS
Enter the seven PLASMIC score components using the patient’s presentation data.
Review the total score together with the aHUS/TTP interpretation in the context of confirmed thrombotic microangiopathy.
Platelet count*Scores 1 point if <30 x10^9/L
x10^9/L
Indirect bilirubinHemolysis if >2 mg/dL
mg/dL
ReticulocytesHemolysis if >2.5%
%
Haptoglobin undetectable
HaptoglobinOptional; hemolysis if ≤10 mg/dL
mg/dL
No active cancer in the past year*
No history of solid organ or stem cell transplant*
Mean corpuscular volume*Scores 1 point if <90 fL
fL
International normalized ratio*Scores 1 point if <1.5
