HSCT-Associated Thrombotic Microangiopathy Diagnostic and High-Risk Features Calculator

Applies prospective diagnostic criteria for hematopoietic stem cell transplant–associated thrombotic microangiopathy and identifies high-risk features linked to poor survival.

Test 1: Lactate dehydrogenase above upper limit of normal for age*

Test 1: De novo thrombocytopenia*

Test 1: De novo anemia*

Test 1: Microangiopathy*

Test 1: No coagulopathy*

Test 1: Coombs test negative*

Test 2: Lactate dehydrogenase above upper limit of normal for age*

Test 2: De novo thrombocytopenia*

Test 2: De novo anemia*

Test 2: Microangiopathy*

Test 2: No coagulopathy*

Test 2: Coombs test negative*

ProteinuriaHigh-risk threshold: 30 mg/dL or higher

mg/dL

Urine protein to creatinine ratioHigh-risk threshold: greater than 0.2 mg/mg

mg/mg

sC5b-9

sC5b-9 upper limit of normal

sC5b-9 above upper limit of normal