Pediatric Sequential Organ Assessment Score (pSOFA)

Quantifies the severity of organ dysfunction in critically ill children using age-adjusted subscores across 6 organ systems

Respiratory*

PaO2/FiO2 >400 or SpO2/FiO2 >292+0

PaO2/FiO2 300-399 or SpO2/FiO2 221-292+1

PaO2/FiO2 200-299 or SpO2/FiO2 148-220+2

PaO2/FiO2 100-199 with respiratory support or SpO2/FiO2 67-147+3

PaO2/FiO2 <100 with respiratory support or SpO2/FiO2 <67+4

Coagulation (platelet count)*

>150 ×10^3/µL+0

100-149 ×10^3/µL+1

50-99 ×10^3/µL+2

20-49 ×10^3/µL+3

<20 ×10^3/µL+4

Hepatic (total bilirubin)*

<1.2 mg/dL+0

1.2-1.9 mg/dL+1

2.0-5.9 mg/dL+2

6.0-11.9 mg/dL+3

>12 mg/dL+4

Cardiovascular age band*

<1 monthage_1

1-11 monthsage_2

12-23 monthsage_3

24-59 monthsage_4

60-143 monthsage_5

144-216 monthsage_6

>216 monthsage_7

Cardiovascular*

MAP above the age-specific threshold+0

MAP below the age-specific threshold+1

Dopamine ≤5 mcg/kg/min or any dobutamine+2

Dopamine >5 mcg/kg/min or epinephrine ≤0.1 mcg/kg/min or norepinephrine ≤0.1 mcg/kg/min+3

Dopamine >15 mcg/kg/min or epinephrine >0.1 mcg/kg/min or norepinephrine >0.1 mcg/kg/min+4

Neurologic (Glasgow Coma Score)*

15+0

13-14+1

10-12+2

6-9+3

<6+4

Renal age band*

<1 monthrenal_1

1-11 monthsrenal_2

12-23 monthsrenal_3

24-59 monthsrenal_4

60-143 monthsrenal_5

144-216 monthsrenal_6

>216 monthsrenal_7

Renal (serum creatinine)*

Within age-specific normal range+0

Mild age-specific creatinine elevation+1

Moderate age-specific creatinine elevation+2

Severe age-specific creatinine elevation+3

Very severe age-specific creatinine elevation+4