The VARA-ILD Combined Risk score

Estimates the probability of rheumatoid arthritis–associated pulmonary fibrosis using a 5-variant genetic risk score plus clinical variables from the externally validated modified VARA-ILD-CRS.

Age*Use the patient’s current age.

years

Male sex*

Ever smoker*

Mean DAS28-CRP*Enter the mean DAS28-CRP value when available.

Rheumatoid factor positive*

MUC5B rs35705950 variant allele present*

DSP rs2076295 variant allele present*

LRRC34 rs6793295 variant allele present*

OBFC1 rs11191865 variant allele present*

FAM13A rs2609255 variant allele present*