Medication Regimen Complexity-Intensive Care Unit (MRC-ICU) Score

Quantifies medication regimen complexity in critically ill ICU patients.

AminoglycosidesEnter the number of distinct aminoglycosides, e.g., amikacin, gentamicin, or tobramycin.

Amphotericin B or liposomal amphotericin B

AntiarrhythmicsEnter the number of distinct antiarrhythmics, e.g., amiodarone, dofetilide, or sotalol.

AnticoagulantsEnter the number of direct oral anticoagulants or fondaparinux agents.

AnticonvulsantsEnter the number of distinct anticonvulsants, e.g., carbamazepine, phenobarbital, phenytoin, or valproic acid.

Argatroban

Azole antifungalsEnter the number of distinct azole antifungals, e.g., posaconazole or voriconazole.

Blood productsEnter the number of blood product categories, e.g., factor products or antithrombin III.

ChemotherapyEnter the number of active inpatient chemotherapy agents.

Clozapine

Digoxin

Ganciclovir/valganciclovir

Hyperosmolar fluidsExamples include hypertonic saline and mannitol.

ImmunosuppressantsEnter the number of distinct agents, e.g., cyclosporine, sirolimus, or tacrolimus.

Lidocaine continuous infusion

Lithium

ProstacyclinsEnter the number of distinct agents, e.g., epoprostenol, iloprost, or treprostinil.

Theophylline

Therapeutic heparinsExamples include therapeutic enoxaparin or heparin infusion.

Vancomycin IV

Warfarin

Neuromuscular blockade

Continuous infusionsEnter the number of continuous infusions, excluding agents counted elsewhere.

Parenteral nutrition managed by non-pharmacist service

Parenteral nutrition managed by clinical specialist pharmacist

Thromboembolic prophylaxis

Stress ulcer prophylaxis

Glycemic control

Bowel regimen

Chlorhexidine

Opioids and sedativesEnter the number of scheduled or PRN opioid and sedative agents.

Continuous infusion opioids and sedativesExamples include propofol, fentanyl, dexmedetomidine, ketamine, or benzodiazepine infusions.

AntimicrobialsInclude HIV medications; exclude agents counted elsewhere.

Restricted antimicrobials

Continuous renal replacement therapy

Extracorporeal membrane oxygenation (ECMO)

Intra-aortic balloon pump (IABP) or left ventricular assist device (LVAD)

Mechanical ventilation